Data resource
Cell Model Passports
A reference database and API providing standardized annotations for cancer cell models used in dependency mapping.
- Web App
- Cell models
- DepMap
Resources
A curated directory of PRECISE Consortium resources for studying cancer dependencies, synthetic lethality, buffering interactions, and tumour vulnerabilities.
Software & computational tool
CELLector
A Shiny-based tool for genomics-guided cancer cell line selection and experimental cohort design.
- Software package
- Shiny
- Cell lines
Software & computational tool
CoRe
An R package for identifying core-fitness and common-essential genes from joint analyses of CRISPR-Cas9 viability screens.
- Software package
- R
- CRISPR
Software & computational tool
CRISPRcleanR
An R package for correcting gene-independent copy-number effects and other biases in pooled CRISPR-Cas9 screening data.
- Software package
- R
- CRISPR
Software & computational tool
CRISPRcleanR WebApp
An interactive web application for processing, correcting, and visualizing genome-wide pooled CRISPR-Cas9 screen data.
- Web app
- CRISPR
- Correction
Software & computational tool
E-CRISP
A web tool for designing CRISPR guide RNAs and supporting genome editing experiment setup.
- Web app
- CRISPR
- Guides
Data resource
GenomeRNAi
A database of RNAi and CRISPR screening experiments, reagent annotations, and phenotypic screening results.
- Web app
- RNAi
- CRISPR
Data resource
HT-29 Benchmark
A benchmark resource for evaluating computational methods that correct biases in HT-29 CRISPR-Cas9 screening data.
- Software package
- Benchmark
- CRISPR
Software & computational tool
MIDAA
A deep learning framework for integrating multi-omics data in cancer analysis and model interpretation.
- Software package
- AI
- Multi-omics
Experimental resource
MinLibCas9
A compact pooled Cas9 CRISPR library designed as a practical reagent for scale-limited fitness screening experiments.
- Experimental reagent
- CRISPR
- Library
Software & computational tool
MinTEs
A Snakemake pipeline for processing and analyzing CRISPR screening experiments in a reproducible workflow.
- Workflow
- Snakemake
- CRISPR
Software & computational tool
mobster
A computational tool for subclonal deconvolution and tumor evolution analysis from sequencing data.
- Software package
- R
- Subclones
Software & computational tool
MOSA
A multi-omics variational autoencoder model for generating synthetic DepMap-like profiles and supporting cancer dependency analyses.
- Code repository
- DepMap
- Multi-omics
Data resource
Mutfunc
A database of precomputed variant effect predictions for exploring the molecular consequences of genetic mutations.
- Web app
- Variant effect prediction
- Mutations
Software & computational tool
NeuroVelo
A PyTorch-based computational tool for modeling RNA velocity from single-cell data.
- Software package
- PyTorch
- RNA velocity
Data resource
PhosFate
A web resource for exploring human quantitative phosphoregulation and inferring kinase and protein complex regulation from phosphoproteomics data.
- Web app
- Phosphoproteomics
- Kinase regulation
Data resource
PPI Atlas
A web resource providing predicted protein-protein associations across human tissues and cell types.
- Web app
- Protein-protein interactions
- Proteomics
Data resource
Sanger DepMap Miner
A data portal for exploring functional genomics and cancer dependency datasets from the Sanger DepMap programme.
- Web app
- DepMap
- Genomics